Pre-clinical Unit:

Pre-clinical unit is working for last 20 years in RRIUM, Srinagar with good experience and expertise to design and conduct the toxicity studies with various route of administration viz. oral, dermal, subcutaneous, intraperitoneal and intramuscular in accordance with international guidelines such as OECD, Schedule Y and AYUSH guidelines and the studies are conducted in compliance with Good Laboratory Practices (GLP).

Studies:

  1.  Maximum tolerated dose
  2. Dose range finding
  3. Acute study (Single dose toxicity study)
  4. Sub-acute study (28 days repeated dose study)
  5. Sub chronic study (90 days repeated dose study)

 

 

  • Pathology

The pathology laboratory has two functional areas i.e. Clinical Pathology and Histopathology. The Clinical pathology carries out haematology, clinical chemistry, coagulation and urine analysis which are mandatory in general toxicity evaluation. The histopathology laboratory deals with the necropsy, tissue weighing, grossing, tissue processing, embedding/impregnation and section cutting and in the end pathologist evaluation of microscopic section.

  • Animal holding facility

GLP complied animal holding facility is equipped for small animal experimentation with separate arrangements for quarantine, experimentation rooms, dosing room and necropsy room. Animal experimentation is under the control of the Institutional Animal Ethics Committee (IAEC) of RRIUM, Srinagar which is registered with CPCSEA, Govt. of India with registration No. 927/GO/Re/S/2006/CPCSEA, Dated 14/03/2016. The animal holding facility is equipped with Individual ventilated cages besides that a well-equipped pathology lab, biochemical lab, hematology lab and instrumentation lab.